Closed loop insulin delivery systems reduce type 2 diabetes complications
Researchers said: “The present study shows that fully closed-loop insulin delivery is a safe and effective approach to improve glycaemic control in people with type 2 diabetes during 8 weeks of use in the outpatient setting.
“The closed-loop system improved the proportion of time spent in target glucose range by 35% (an additional 8 hours per day), and reduced mean glucose, compared with standard insulin therapy, without increasing the time spent in hypoglycemia.
“The results of this study build on evidence from a feasibility study evaluating fully closed-loop therapy in people with type 2 diabetes and end-stage renal failure on dialysis.
“Here, we demonstrate that this technology can benefit the wider population with type 2 diabetes requiring insulin and can be safely implemented in the home setting. As a considerable proportion of people with type 2 diabetes struggle to achieve the recommended glycaemic targets with currently available therapies, including insulin therapy, fully closed-loop systems offer a new approach to improve glycaemic outcomes to reduce the risk of long-term complications.”
Researchers concluded: “This study suggests that fully closed-loop insulin delivery is a safe and efficacious approach to manage type 2 diabetes in adults. Larger randomised controlled trials with diverse populations and longer follow-up are required to ensure generalizability across a wider target population and to determine whether it is a cost-effective approach that provides sustained benefits for people with type 2 diabetes requiring insulin therapy.”
Read the report in Nature
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